Note: The health effects are highly dependent on the manner and degree of exposure and on the exact chemical 'species' in which the nickel atoms are present.The allergic effects tend to arise from the Nickel cation Ni ++, but it is not entirely clear which chemical species is reponsible for the carcinogenic effects noted much more commonly in the past. Exposure to nickel may lead to cancer. If nickel enters the body with nickel contaminated air it is retained in the lungs. Nickel is a common metal that can cause many of these problems. The Effects of Nickel on Human Health. Chronic noncancer health effects may result from long-term exposure to relatively low concentrations of pollutants. About 10% of women and 2% of men are highly sensitive to nickel. Health effects. First, nickel causes essential metal imbalances and severely disrupts enzyme action and regulation. The aim of this paper is to discuss the sources of Nickel in the body as well as the systemic adverse effects of Nickel as a degradation product of stainless steel surgical implants. Some of these toxic symptoms include: Cancer: Prolonged exposure to nickel, when seen as an occupational hazard, my result in cancer of nose and throat. Nickel deficiency can cause diseases such as diabetes, anemia, cirrhosis, uremia, renal failure, abnormal metabolism of liver lipids and phospholipids. Exposure can harm the lungs, stomach, and kidneys. Normally, the adult body contains about 10mg of nickel. A nickel allergy is the body’s adverse immune response when someone comes into contact with a product containing nickel. Nickel deficiency has not been reported in people, although it may exist, since nickel deficiency has been seen in animals. Nickel has been found to have some adverse systemic effects on the body. The patient may experience asthma attacks, pulmonary fibrosis , and chronic bronchitis . Nickel (Ni) is a hard, silvery-white metal that may cause irritation to the skin. Certain amounts of nickel are useful to the human body, but too much nickel can be toxic. Preventing nickel levels in the body from getting too low (nickel deficiency). Workers may be harmed from exposure to nickel. Inhalation of nickel also can cause cancer of the lungs, nose and sinuses. General Nickel Toxicity Information Nickel is a silver-white metal found in the earth’s crust that is used to produce steel, nickel-cadmium batteries, heating fuel, nickel plating and ceramics. If you've been exposed to large amounts of nickel, and believe it to be affecting your health, it is important to take proper measures to get your body back in balance. Taking trace amounts of nickel in a supplement is effective for preventing nickel deficiency. 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